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Movement: Add 30 minutes of daily activity (walking, exercise, etc.) to accelerate fat burning
The honest summary: this is a theoretical concern based on mechanism, not a documented adverse event
Lifestyle factors: Alcohol use, poor diet, or chronic stress can deplete stores faster, requiring closer session spacing
317,318 Additionally, resistant CSCs can secrete small extracellular vesicles (sEVs) carrying phosphorylated PKM2 (pY105-PKM2), which reprogram recipient cells to acquire stem-like traits and chemoresistance
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