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Hydroxychloroquine and lupus flare: a good drug, but we need to do better

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MC3R/MC4R selectivity and center channel PT-141 primarily targets MC3R and MC4R receptors located in the hypothalamus

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Long-term effectiveness requires continued treatment for sustained results

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[17] Metabolic sequelae include dyslipidemia (particularly elevated LDL-C) and, less commonly, hypertension or ischemic cardiac events

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