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There is a discontinuation rate of around 10%
Important observations All five clinical trials that were included in the analysis reported GLP-1 receptor agonist-mediated reduction in substance use disorder, with two trials respectively reporting a significant therapeutic impact of GLP-1 receptor agonist in reducing alcohol use disorder and nicotine use disorder
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Ogawa Y, Kurosu H, Yamamoto M et al (2007) Beta Klotho is required for metabolic activity of fibroblast growth factor 21
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