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The Institutional Animal Care and Use Committee of the Institute for Basic Science (Daejeon, South Korea) approved all animal care and experimental procedures
To study the permeability of nanoparticles in vitro BBB models, which conform to the 3R principles with the minimalization the number of animal experiments, are widely used either in static [34] or in dynamic conditions by employing lab-on-a-chip systems [35]
A small needle is inserted in your arm and the fluid drips slowly into your blood
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