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If you have an underlying health condition like kidney disease, or if you take medication that interferes with B6 metabolism or absorption (such as oral contraceptives, hypertension drugs like hydralazine, and others), ask your doctor about appropriate supplement dosing

The key is consistent, regular injection

George Hoyt Whipple of the University of Rochester ran an experiment, showing that the administration of liver rapidly restored the blood counts of dogs he had made anemic by making them bleed

For individuals significantly above 250 pounds, extended protocols of 16-20 weeks rather than higher daily doses often produce better outcomes