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Although prior work indicates that ferroptosis acts as a central hub linking reactive oxygen species to autophagy and apoptosis, this study does not establish its priority within the cascade of oxidative stress, neuroinflammation, and multimodal cell death, particularly regarding microglial ferroptosis and its contribution to secondary neuronal injury
In addition, serum toxic advanced glycation end-products (TAGE), biomarkers of vascular wall damage, were markedly reduced across all participants
This can increase physical performance and exercise recovery
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