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The fact that L-carnitine supplementation didn`t add to the patients` seizure control was previously reported by Selter and collaborators who studied carnitine supplementation as one of dietary modifications to improve seizure control in patients on KDT and reported that this dietary modification wasn`t ideal for improving seizure control 24
In animal studies, offspring with prenatal exposure to valproate had malformations similar to those seen in humans and demonstrated neurobehavioral deficits [seeUse in Specific Populations (8.1)]
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