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GLP1-GIP receptor co-agonists: a promising evolution in the treatment of type 2 diabetes
1.) Discussion Our study demonstrates that arGLP-1 are a highly effective and well-tolerated option for managing IWL, WR, and improvement of comorbidities following bariatric surgery
The long half-life is driven by albumin binding (greater than 99% bound), reduced DPP-4 degradation due to the Aib8 substitution, and slowed renal clearance of the larger albumin-bound complex
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