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Major guidelines, including the American Diabetes Association and obesity medicine societies, acknowledge that: Continuing treatment maintains benefits Stopping leads to regain for many people Decisions should be individualised and shared Some people will choose long-term treatment
Hauck, 2003)
26,34,35 In parallel, TCP, defined as the ability of cancer cells to reversibly adopt alternative phenotypic states, including EMT, lineage transdifferentiation, and acquisition of stem-like features, confers phenotypic flexibility that enables drug tolerance
The impact of increasing body mass index on in vitro fertilization treatment, obstetrical, and neonatal outcomes
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