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This captures cases where side effects were severe enough to warrant stopping treatment entirely

In SELECT, a trial of adults with overweight or obesity and established cardiovascular disease but no diabetes, once-weekly semaglutide 2.4 mg cut the primary composite of cardiovascular death, nonfatal heart attack, or nonfatal stroke to 6.5% versus 8.0% on placebo a hazard ratio of 0.80, roughly a 20% relative reduction

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