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Half-life comparison Semaglutide has an elimination half-life of approximately 7 days, or 168 hours
N Engl J Med 384(11):9891002 Frias JP et al (2021) Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes
Gathering progress notes, lab results, imaging reports, and medical necessity letters from the ordering physician
they do not indicate a dangerous response and typically warrant dose continuation rather than discontinuation, though you should always report persistent concerns to your PlexusDx provider
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