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(2021) reported that lactate-induced histone lactylation (H3K23la) contributes to uterine endometrial remodeling and supports early embryonic development, underscoring its regulatory role in reproductive physiology [85]

226 It is activated through two major branches, the canonical (IB-dependent) and noncanonical (NIK-dependent) pathways, both of which are frequently dysregulated in tumors and their microenvironments

After ischemic injury, astrocytes can donate functional mitochondria to damaged neurons, thereby supporting neuronal survival in experimental models [31]