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In the context of AD, the focus should be on individuals at risk, such as those with MCI, subjective cognitive decline, elders with positive A or tau biomarkers, APOE -4-carriers or healthy elderly individuals with high-risk scores [105]
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All assays were performed in 96-well plates using the respective commercial kits according to the manufacturers protocols, with appropriate sample dilutions and standard curves
The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications
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