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Hyperpigmentation: By inhibiting MMPs and ROS, it may lighten age spots and UV- induced discoloration
The peptide inhibits nuclear factor-B (NF-B) activation, a master regulator of inflammatory gene expression, while simultaneously activating peroxisome proliferator-activated receptor- (PPAR-), which promotes inflammatory resolution
The compound exists as a research peptide without established clinical safety data in humans
If the vitamin B12 is ingested in its protein bound form, then it must first undergo a proteolytic cleavage in the stomach or duodenum where it will bind to an R-binder and then enter into the duodenum for further cleavage.1,2,8 This proteolytic cleavage is mostly dependent on the functional activity of pepsin
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