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Previous studies in animal models and in ALS patients showed that injections of ultrahigh-dose methylcobalamin, a naturally occurring form of vitamin B12, could help improve the transmission of nerve signals between the brain and muscles

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After a single intravenous (IV) administration, single intramuscular (IM) administrations at three doses in successive increments along with repeated IM administrations, the elimination half-life (t 1/2 ) of prototype BPC157 was less than 30 min, and BPC157 showed linear pharmacokinetic characteristics in rats and beagle dogs at all doses