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The trade-off is pharmacokinetic: oral delivery subjects the peptide to stomach acid (pH roughly 1.5-2.0 fasting) and proteolytic enzymes including pepsin and pancreatic proteases before any absorption can occur

The current standard treatment for patients with breast cancer includes the combination of surgery, radiation, hormone therapy and chemotherapy drugs, such as anthracyclines, cyclophosphamide, taxanes and platinum compounds [2, 3]