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The ability of MEDI4166 to improve glycaemic control in a model of Type 2 diabetes was investigated in male db/db mice following weekly injections of MEDI4166 at 3, 10 or 30 mg/kg over a 4 weeks period
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For instance, the outcomes of semaglutide and liraglutide in patients with DM2 have shown a cardiovascular risk factors reduction and an improvement in glucose levels and nutritional status (22, 58, 6163)
In this local model, the peptide functions a bit like certain foods that boost satiety hormones or stimulate gut-to-brain signals
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