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General anesthesia triggered gene expression changes consistent with astrocytes being in a low-activity environment, but additionally caused induction of a reactive profile, with transcriptional changes enriched in those triggered by stroke, neuroinflammation, and A/tau pathology
Omega-3 fatty acids, curcumin, and N-acetylcysteine may provide synergistic anti-inflammatory benefits
Robert Doyle at Syracuse University, our labs created a conjugated GLP-1R agonist (Cbi-Ex4) with reduced brain penetrance
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