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In contrast, semaglutide is a GLP-1 receptor agonist that stimulates insulin secretion and slows gastric motility, lowering glucose levels
Start Retatrutide first, establish your baseline response over 2 to 4 weeks, then layer in MOTS-C
Tirzepatide acts on GLP-1 receptors, but it is not solely a GLP-1 peptide
The choice often comes down to: Cost considerations (especially for cash-pay patients) Side effect profiles (individual tolerance) Patient preference after discussing options Insurance coverage (whats actually accessible) Providers like TrimRx offer both options, allowing you and your healthcare provider to choose based on your specific situation rather than being limited by insurance restrictions
