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The FDA approved sitagliptin, the first DPP-4i on the market, in 2006 and shortly after, numerous additional DPP-4i received market clearance
The recommended dose of L-carnitine is 15 g/day for healthy individuals (123) and 100400 mg/kg/day for patients with carnitine deficiency (96)
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Dosage requirements : Treatment typically starts at a lower dose and escalates to therapeutic levels over several weeks
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