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It is possible that androgen/AR signaling first acquires ARA55 as a transcriptional coactivator to increase the expression of various collagens and their receptors to maintain the balance of ECMintegrin interactions, which may then activate the FAK via increasing the formation of focal adhesion complex to promote the migration of PDCs
S., Garzon, S., Casarin, J., Franchi, M., & Ghezzi, F
Nature 535 , 182186 (2016)
This patient population has a higher risk of cardiovascular death, heart attack and stroke
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