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Further studies are needed to test the exact mechanisms by which MPTP causes the accumulation of succinate and the role of succinate in MPTP-induced RET activation
References Averill-Bates DA
Patents and pharmaceutical interest: Washington State University researchers patented Dihexa for potential use in Alzheimers and dementia therapies, but no pharmaceutical company has taken it through regulatory development
Financial support and sponsorship This work was supported by grants from the National Science Foundation ( IOS-1557341 (HFN, MCR) and DMS-2038056 (AC)
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