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Two caveats temper the result: nausea occurred in 46% of lixisenatide-treated participants and vomiting in 13%, raising the possibility of functional unblinding, and the MDS-UPDRS is a clinical scale rather than a direct measure of dopaminergic neuron survival

A 6mg/mL concentration (30mg vial in 5.0mL) would require a 2mL injection for a 12mg dose, which is within the standard range for subcutaneous administration