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3.4 TTO analysis of dermatologic AEs by AIs The onset times for 10 PTs (alopecia, bullous dermatitis, dry skin, erythema, abnormal hair growth, hyperhidrosis, night sweats, pruritus, rash, and urticaria) were significantly associated with anastrozole
A striking feature of these emerging therapies is the use of highly potent topoisomerase-I inhibitors, particularly exatecan, as the cytotoxic payload
As PCOS is often associated with insulin resistance and irregular ovulation, these effects may indirectly support fertility
This contributes to national pharmacovigilance and helps the MHRA identify emerging safety signals from unregulated products
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