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Findings included: Average body weight reduction: 18.3% Average leg volume reduction (perometry): 11.4% Pain reduction (VAS score): improved from 6.2/10 to 3.1/10 on average 12 of 18 patients (67%) reported subjective softening of previously firm, nodular tissue While case series aren't definitive evidence, the leg volume reduction of 11.4% is notable because lipedema fat typically shows minimal response to weight loss interventions

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One survey found that just 20% of companies with over 200 workers cover weight loss drugs, with only 43% of those with 5,000 employees or more doing so