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For example, according to a meta-analysis of randomised controlled trials, therapies with GLP-1 receptor agonists significantly reduced cardiovascular events and improved cardiometabolic parameters
The trial used unmodified GLP-1 without absorption enhancers, without nanocarrier formulations, without any of the technologies that modern intranasal peptide research employs to improve bioavailability
FDA warning letters to 30 compounders, the Hims/Novo Nordisk settlement, and ongoing pharmaceutical litigation signal tightening oversight of the compounded GLP-1 market
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