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10.1111/j.1467-789X.2004.00152.x 60 MazzaE.TroianoE.FerroY.LissoF.TosiM.TurcoE.et al (2024)

In a real-world study of more than 20,000 adults using tirzepatide for weight loss (without diabetes): About 74% of people stayed below 10 mg even after six prescription fills Most used 2.5 mg to 7.5 mg weekly On average, participants lost nearly 12% of their body weight after six months, even without reaching higher doses These findings suggest that, for some individuals, smaller weekly doses can still be effective, especially when combined with consistent lifestyle changes

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Behavioral therapy: CBT, motivational interviewing, structured weight-loss programs