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Accessed 4/15/16
No noticeable effect: in research terms, FOXO4-DRI only acts where senescent cells are present, and degraded or mislabeled product loses activity
This study innovatively focuses on the mechanism by which FOXO4-DRI induces apoptosis in senescent endothelial cells, demonstrating that it functions by activating the p53/BCL-2/Caspase-3 signaling pathway to promote selective apoptosis of these cells
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