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Because this side effect occurs consistently, it has led to interest in topiramate for obesity, but the risks associated with the drug make off-label use for weight loss inappropriate outside specialist settings
The next inflection is whether higher exposure preserves the CNS-sparing safety profile while delivering a clear PK step-up
Calculating doses incorrectly Use calculators : Don't eyeball measurements
The metabolomic analysis, which was performed to assess the mechanisms of the improvement of fatty liver by L-carnitine in more detail, demonstrated a 4.4-fold increase in the amount of L-carnitine found in the liver following L-carnitine administration
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