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Taken together with the findings that utilization of esketamine as an antidepressant increases LAC levels [59], the fact that the decrease in LAC levels in subjects with MDD is independent of psychotropic drug treatment raises the possibility that increasing LAC levels may be needed to induce antidepressant effects

Key takeaways Semaglutide is a GLP-1 receptor agonist that helps lower blood sugar levels for people with diabetes