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Both agents target glucose homeostasis through different mechanismsberberine activates AMPK and improves insulin sensitivity, while GLP-1 agonists enhance insulin secretion and slow gastric emptying, creating potential synergy rather than direct antagonism
Neuropsychopharmacology 43, 20002008
At a 5mg/mL concentration, 2 extra units equals 0.1mg of additional semaglutide
Now, there's certainly a catch up race among other pharmaceutical companies who weren't doing this to now try to get into it and see if they can compete
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