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If you have any of the following, make sure to talk about it with your doctor: A history of pancreatitis Severe gastrointestinal diseases You are pregnant or breastfeeding A personal or family history of medullary thyroid cancer or multiple endocrine neoplasia If youre undergoing surgery, you may need to stop taking GLP-1 beforehand

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Treatment response may be affected by: the dose reached the length of treatment side effects and tolerability dietary intake physical activity sleep medical conditions current medicines adherence to treatment individual biology Semaglutide begins affecting appetite and blood-glucose regulation after treatment starts, but noticeable weight loss can take time