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Circulating microbial metabolites and immune mediators can access systemic circulation and interact with the bloodbrain barrier (BBB), endothelial cells, and resident immune cells
Are expectations realistic
MTX treatment caused a prominent dilatation of tubules and degeneration in tubular cells, marked vascular and glomerular congestion, dilatation in Bowmans space and inflammatory cell infiltration in the interstitium (Fig
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