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A 2024 review in BioImpacts synthesizing the topical GHK-Cu evidence concluded that the peptide has consistent anti-wrinkle and skin-rejuvenating activity in human studies, though formulation and delivery remain ongoing challenges [5]
The peptide demonstrates an interesting property of migrating toward areas of tissue damage throughout the body
That said, the combination itself has not been clinically validated there are no controlled human trials of this specific blend, and the supporting data for each peptide is largely preclinical (animal) work and anecdote
Vojdani A, Vojdani E, Kharrazian D
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