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These effects are typically mild and improve as your body adjusts
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Lets start with how these medications work: Semaglutide: This injectable medication is a GLP-1 receptor agonist that works by regulating your appetite and reducing your food intake
For some patients this may not be practical, and currently there are no data regarding the efficacy of oral semaglutide with dosing conditions (e.g., different times or fasting periods) other than those used in the PIONEER trials
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
