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In humans and other mammals, L-carnitine deficiency causes severe hyperlipidaemia and systemic metabolic syndrome 5,6

It was found that Alzheimers patients that were randomly assigned to the acetyl l-carnitine group (ingesting 2.5-3g daily) again had a slower rate of deterioration in a range of neuropsychological parameters

This results in an increase in the cytoplasmic calcium concentration, which enhances insulin secretion from -cells [24,25,26] (Fig