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CagriSema is a fixed-dose combination of two medications in a single once-weekly injection: cagrilintide (2.4 mg), a long-acting amylin analog, and semaglutide (2.4 mg), the same GLP-1 receptor agonist found in Wegovy and Ozempic

By inhibiting NNMT, the compound shifts cellular metabolism away from fat storage and toward fat burning

Transfected cells were seeded onto glass bottom MatTek dishes, imaged live at 37C in RPMI-1640 without phenol red under vehicle conditions or following stimulation with 1 M exendin-4 and images analysed as previously described (87) with some changes