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In research and cosmetic contexts, GHK-Cu has been associated with tightening loose skin, repairing protective skin barrier proteins, and improving skin firmness, elasticity, and clarity

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However, when there is an excess amount of cytosolic DA outside of the synaptic vesicle in damaged neurons, i.e., after L-DOPA treatment, DA is easily metabolized via monoamine oxidase (MAO) or by auto-oxidation to cytotoxic ROS (Zucca et al., 2014)

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