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Description

Its cysteinyl thiol group neutralizes reactive oxygen species, donates electrons in glutathione peroxidase reactions, and forms conjugates with electrophilic xenobiotics via glutathione S-transferases

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Pharm, MSc

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GCGR activation, represented in green, is unique in that glucagon receptors are robustly expressed on hepatocytes, enabling direct liver-directed metabolic effects - a mechanistic feature absent from both GLP-1R and GIPR signaling

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A priority score between 8 and 10, 57 or 04 represents the signal with strong, moderate or weak clinical priority, respectively

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