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Because SJS affects your skin and mucous membranes, those areas are at risk for complications, which can include: skin pigment changes scarring of the esophagus, genitals, or other areas cellulitis eye conditions, like dryness, photophobia, and blindness detachment and loss of nails mouth conditions, like dry mouth, periodontal disease, and gingivitis scalp hair thinning You can also experience severe complications from SJS inside of your body, including: sepsis gastrointestinal bleeding pulmonary embolism pulmonary edema heart attack respiratory failure liver failure kidney failure pulmonary complications, like bronchitis, bronchiectasis, and respiratory tract obstruction If you receive a diagnosis of SJS, youll immediately be admitted to a hospital, potentially the intensive care unit (ICU), a specialized burn unit, or dermatology unit