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Wegovy (semaglutide) is a GLP-1 receptor agonist weight loss medication approved by the U.S
doi:10.1002/nbm.4227 112. Shimizu, T., Iwanaga, M., Yasunaga, A., Urata, Y., Goto, S., Shibata, S., & Kondo, T
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Consistently, AMPK activator AICAR was attenuated, while PARP-1 over-activation aggravated cholesterol-induced toxicity in INS-1 cells, indicating that in islet cells, PARP-1 also regulates cholesterol efflux through AMPK activation and ABCA1 protein, therefore affecting the GLP-1 protection against cholesterol-induced toxicity
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