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Instead of climbing the ladder until side effects push back, you stay near the bottom, sometimes below the bottom rung entirely, and only move when your body gives you a reason to
Metformin is a biguanide anti-hyperglycaemic agent which decreases liver glucose production and increases tissue insulin sensitivity [4]
Finan B, Clemmensen C, Zhu Z et al (2016) Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease
The prescribing physician may recommend additional supportive measures if nausea persists
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