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Outside the brain, dopamine is synthesized in several tissues including the gastrointestinal system where its actions reduce gastrointestinal motility, the pancreas where its actions inhibit insulin synthesis, and in the kidneys where its actions increase sodium excretion and urinary output
Lee DH, Lee IK, Song K, Steffes M, Toscano W, Baker BA, Jacobs DR Jr
The clinical manifestations of symmetrical joint involvement include arthralgia, swelling, redness, and even limiting the range of motion
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