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Implications for diabetes treatment While GLP-1 is typically made in the gut, the study confirms that alpha cells in the pancreas can also release GLP-1into the bloodstream after eating, helping to lower blood sugar by increasing insulin and reducing glucagon levels
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These findings are investigational
Clinical trials such as SURMOUNT-1 have demonstrated average weight loss of 15-21% of body weight over 72 weeks (depending on dose), with much of this effect attributed to reduced caloric intake
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