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10.1016/j.celrep.2018.05.009 Cell Rep

The result is typically severe nausea, vomiting, or both, because they stacked the side effects of rapid escalation onto a body that had not yet reached steady state at the previous dose

Most of it happens in the first 6 months after stopping, then decelerates

A larger meta-analysis encompassing over 77,000 participants similarly reported a reduced overall risk of respiratory diseases with GLP-1 receptor agonist treatment, but pulmonary fibrosis was not analysed as a discrete outcome, and no fibrotic endpoints were prospectively assessed [64]