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For example, due to the downregulation of genes for purinergic receptors (e.g., P2ry12 ) and potassium leak channels (e.g., Thik-1 ) in aged mice, the ability for microglia to sense hyperactive neurons and migrate toward them in order to facilitate rapid repolarization would be reduced, impairing their beneficial modulation (Hickman et al., 2013
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(bron) Een bijzonder kenmerk is dat glutathion zichzelf kan recyclen: het kan, na binding aan een stof, weer hersteld worden tot zijn actieve vorm
Group 4 transporters are involved in the efflux of sulfate from the vacuoles, whereas the function of Group 5 sulfate transporters is not known yet, and likely function only as molybdate transporters
