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Doses greatly exceeding the nutritional requirements (for example, hundreds of milligrams daily) have not been studied in randomized trials for safety, so one should avoid mega doses in pregnancy unless treating a specific condition (such as pyridoxine-responsive seizures) under careful supervision
Approved institutional accounts can also order against a purchase order under net-30 terms, with Canadian-dollar invoicing applied throughout
This ensures safety and appropriate dosing for each individual patient
There is no single number that answers this for everyone
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