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The most commonly reported adverse effects in Phase 2 trials were gastrointestinal in nature, including: Nausea (the most frequently reported) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally dose-dependent and most pronounced during dose escalation, typically improving over time
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Zepbound (tirzepatide) works on two gut-hormone receptors, GLP-1 and GIP, and is often grouped with the GLP-1 medications as shorthand
Q5: Can GLP-1s be used for non-diabetic weight loss
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