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Once the protein loses its shape, it can no longer fit into the receptors in your body properly
Young: Yeah, tirzepatide got lifted off of the shortage list in, I think, late 2024, and then semaglutide followed in 2025
GLP-1 for weight loss Medically reviewed by Dr Crystal Wyllie Last reviewed: 19 Jun 2026 Glucagon-like peptide-1 (GLP-1) agonists are a popular weight loss treatment in the UK
This can eventually lead to prediabetes and type 2 diabetes
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