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One study found that sleep deprivation reduces total glutathione levels in the hypothalamus, which produces the hormones that regulate many of our basic bodily functions
The pioneer work of Wilcken and Wilcken (1976) showed an abnormal increase in homocysteine after an oral methionine load in patients with coronary artery disease
Clinically stable patients with BD showed significantly lower leukocyte mitochondrial DNA copy number and higher mitochondrial oxidative damage compared with participants without any psychiatric illness [38]
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